Life Extension Cosmesis Skincare Skin Firming Complex, 1 oz | Tightener | 80166

Life Extension

SKU: 80166


Skin Firming Complex


Get tighter, younger-looking skin

1 oz. (30 ml) 
Item# 80166


Firming and tightening skin has been a challenge. Cosmesis Skin Care has developed Skin Firming Complex, a multi-nutrient serum that lifts and tightens skin on the face and neck area for visibly firmer, more defined, younger-looking skin.

Benefits at a Glance:

  • Palmitoyl peptides support collagen synthesis.
  • Helps soften the appearance of wrinkles and fine lines.
  • Plant stem cell extracts promote a healthy response to environmental exposure.
  • Boosts adenosine triphosphate (ATP) energy for skin rejuvenation.
  • Snail mucin supports skin smoothness and hydration.
  • Hyaluronic acid keeps skin supple, firm, and hydrated.
  • Silicates make skin tighter and firmer.
  • Palmitoyl peptides support collagen synthesis

Palmitoyl tetrapeptide-7 and palmitoyl tripeptide-1 stimulate new collagen synthesis in specialized skin cells known as fibroblasts. These peptides also inhibit the inflammatory response to environmental exposure in the skin to impede the breakdown of existing collagen.1

This makes both peptides fighters against the appearance of wrinkles. In one study, palmitoyl tetrapeptide-7 along with another oligopeptide reduced the depth and volume of wrinkles by 15% and 18%, respectively, as well as improved skin roughness and tone after two months of daily application.2

Softens the appearance of fine lines and wrinkles

Excessive muscle contractions from everyday facial expressions like squinting, frowning, and laughing are also an underlying cause of wrinkles. Researchers have developed several peptides — including acetyl-hexapeptide-8, acetyl octapeptide-3, and pentapeptide-18 — that interfere with several steps of neurotransmitter release to relax muscle contractions and inhibit the appearance of fine lines and wrinkles.3-5

In a clinical trial lasting 14 weeks, a serum containing acetyl-hexapeptide-8 and acetyl octapeptide-3 significantly improved the appearance of facial lines, facial wrinkles, eye lines, and eye wrinkles compared to baseline in participants with mild to moderate exposure-damaged facial skin.6 When researchers applied a cream containing pentapeptide-18 twice a day to the aging facial skin of human volunteers between the ages of 39 and 64, they observed an 11.6% reduction in the appearance of wrinkle depth.5

Healthy cellular energy boost

Three plant stem-cell extracts and their specific secondary metabolites — açaí palm (ferulic acid), Quercus alba (tannic acid), and Perilla frutescens (rosmarinic acid) — stand out for their substantial pro-inflammatory response and antioxidant activity.7-9 In-vitro studies reveal that these plant stem-cell extracts and their secondary metabolites support collagen in human skin.

These same plant stem cell extracts also raise energy stores in the form of adenosine tri­phosphate (ATP) to boost cellular metabolism and increase collagen synthesis.7-9 Human studies show that all three plant stem-cell extracts increase the ability of aging skin to retain water, with this dynamic moisturizing effect observed just 24 hours after application.7-9

Snail mucin supports skin smoothness and hydration

Snail mucin contains superoxide dismutase (SOD), the skin's primary antioxidant defense. This novel compound increases skin matrix remodeling and assembly, and also inhibits the expression of several matrix metalloproteinases (MMPs) that break down elastin and collagen. Mucin promotes dermal fibroblast survival and proliferation as well.10

These multiple mechanisms have translated into impressive skin benefits in humans. Daily application of snail mucin for three months in patients with aging facial skin reduced coarse periocular and the appearance of fine wrinkles.11

Hyaluronic acid supports skin suppleness, firmness, and hydration

Hyaluronic acid is a molecule that adds volume and fullness to skin owing to its superb moisture-binding properties.12,13 When considering that it also plays a significant role in tissue rejuvenation and blood vessel formation, it becomes clear that replenishing hyaluronic acid as we age is a factor in retaining youthful skin.14

Silicates make skin tighter and firmer

A naturally occurring mineral in purified clay works to retract the skin to leave it visibly tighter and firmer. The combina­tion of this natural tightening agent with a biopolymer operate through a similar mechanism to produce a powerful lifting and tightening effect that occurs within minutes after application.

In dermatologist test cases, over 90% of patients using this combination noticed the onset of tightening and firming skin within three to five minutes after application.15

Use Cosmesis Skin Firming Complex regularly for firmer, tighter, and more youthful looking skin!



Purified Water, Sodium Silicate, Magnesium Aluminum Silicate, Acai (Euterpe oleracea) Fruit Extract, Perilla Frutescens Extract, White Oak (Quercus alba) Bark Extract, Lactobacillus Ferment, Palmitoyl Tripeptide-1, Glycerin, Palmitoyl Tetrapeptide-7, Acetyl Octapeptide-3, Acetyl Hexapeptide-8, Pentapeptide-18, Sodium Hyaluronate, Caprylyl Glycol, Snail Secretion Filtrate, Cellulose Gum, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate.


  • Apply 1 to 2 drops to clean skin on areas of concern. Use morning and evening.

Keep out of reach of children. For external use only. Avoid contact with eyes. If product contacts eyes, rinse thoroughly with water. If rash or irritation occurs, please discontinue use.




These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.